ROBO3

Roundabout homolog 3 is a protein that in humans is encoded by the ROBO3 gene.^[5][6]

ROBO3
Identifiers
Aliases	ROBO3, HGPPS, HGPS, RBIG1, RIG1, roundabout guidance receptor 3, HGPPS1
External IDs	OMIM: 608630; MGI: 1343102; HomoloGene: 32119; GeneCards: ROBO3; OMA:ROBO3 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.2 Start 124,865,432 bp[1] End 124,881,471 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A4 Start 37,326,965 bp[2] End 37,344,542 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube left ovary right ovary vena cava sural nerve left uterine tube Amygdala right frontal lobe tendon of biceps brachii C1 segment Top expressed in gray matter layer of cerebellum superior frontal gyrus primary visual cortex nerve fascicle rhombic lip habenula outer nuclear layer embryo inner nuclear layer secondary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding cell-cell adhesion mediator activity Cellular component integral component of membrane axon membrane plasma membrane Biological process multicellular organism development chemotaxis cell differentiation axon midline choice point recognition Roundabout signaling pathway nervous system development axon guidance homophilic cell adhesion via plasma membrane adhesion molecules chemoattraction of axon dendrite self-avoidance commissural neuron axon guidance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64221 19649 Ensembl ENSG00000154134 ENSMUSG00000032128 UniProt Q96MS0 Q9Z2I4 RefSeq (mRNA) NM_022370 NM_001164767 NM_011248 RefSeq (protein) NP_071765 NP_001357285 NP_001357286 NP_001357287 NP_001357288 NP_001357290 NP_001357293 NP_001357295 n/a Location (UCSC) Chr 11: 124.87 – 124.88 Mb Chr 9: 37.33 – 37.34 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse