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ROCK2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ROCK2
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Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. [5]Fasudil is an inhibitor of ROCK protein.

Quick Facts Available structures, PDB ...
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Function

The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

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