RPH3AL

Rab effector Noc2 is a protein that in humans is encoded by the RPH3AL gene.^[5][6]

RPH3AL
Identifiers
Aliases	RPH3AL, NOC2, rabphilin 3A-like (without C2 domains), rabphilin 3A like (without C2 domains)
External IDs	OMIM: 604881; MGI: 1923492; HomoloGene: 5078; GeneCards: RPH3AL; OMA:RPH3AL - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.3 Start 212,389 bp[1] End 386,254 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B5 Start 75,721,825 bp[2] End 75,829,255 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas anterior pituitary islet of Langerhans right adrenal gland left adrenal cortex sural nerve right adrenal cortex right lobe of liver gonad right lobe of thyroid gland Top expressed in primary oocyte islet of Langerhans zygote epithelium of stomach secondary oocyte otolith organ utricle pituitary gland Paneth cell external carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding metal ion binding cytoskeletal protein binding protein binding calcium-dependent phospholipid binding LIM domain binding Cellular component cytoplasm secretory granule membrane membrane transport vesicle membrane secretory granule cytoplasmic vesicle plasma membrane intracellular anatomical structure Biological process glucose homeostasis regulation of exocytosis positive regulation of protein secretion intracellular protein transport negative regulation of G protein-coupled receptor signaling pathway exocytosis regulation of calcium ion-dependent exocytosis positive regulation of insulin secretion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9501 380714 Ensembl ENSG00000181031 ENSG00000262334 ENSG00000282013 ENSMUSG00000020847 UniProt Q9UNE2 Q768S4 RefSeq (mRNA) NM_001190411 NM_001190412 NM_001190413 NM_006987 NM_001291159 NM_029548 RefSeq (protein) NP_001177340 NP_001177341 NP_001177342 NP_008918 NP_001278088 NP_083824 Location (UCSC) Chr 17: 0.21 – 0.39 Mb Chr 11: 75.72 – 75.83 Mb PubMed search [3] [4]
Wikidata
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Interactions

RPH3AL has been shown to interact with RAB27A.^[7][8]