RRAGA

Ras-related GTP-binding protein A is a protein that in humans is encoded by the RRAGA gene.^[5][6][7]

RRAGA
Identifiers
Aliases	RRAGA, FIP-1, FIP1, RAGA, Ras related GTP binding A
External IDs	OMIM: 612194; MGI: 1915691; HomoloGene: 68522; GeneCards: RRAGA; OMA:RRAGA - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p22.1 Start 19,049,427 bp[1] End 19,051,025 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 C4 Start 86,493,905 bp[2] End 86,495,522 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in paraflocculus of cerebellum frontal pole Brodmann area 10 middle frontal gyrus cerebellar vermis islet of Langerhans smooth muscle tissue Skeletal muscle tissue of biceps brachii Skeletal muscle tissue of rectus abdominis Brodmann area 9 Top expressed in zygote secondary oocyte dorsomedial hypothalamic nucleus visual cortex primary visual cortex superior frontal gyrus lateral hypothalamus paraventricular nucleus of hypothalamus choroid plexus of fourth ventricle ventricular zone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein homodimerization activity GTP binding phosphoprotein binding protein binding GTPase activity ubiquitin protein ligase binding protein heterodimerization activity Cellular component cytoplasm cytosol GATOR1 complex lysosomal membrane lysosome nucleus Gtr1-Gtr2 GTPase complex Biological process cellular response to amino acid starvation cell death positive regulation of cytolysis positive regulation of TORC1 signaling modulation by virus of host process cellular response to amino acid stimulus viral process negative regulation of autophagy positive regulation of TOR signaling apoptotic process protein ubiquitination regulation of macroautophagy cellular response to starvation regulation of autophagy Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10670 68441 Ensembl ENSG00000155876 ENSMUSG00000070934 UniProt Q7L523 Q80X95 RefSeq (mRNA) NM_006570 NM_178376 RefSeq (protein) NP_006561 NP_848463 Location (UCSC) Chr 9: 19.05 – 19.05 Mb Chr 4: 86.49 – 86.5 Mb PubMed search [3] [4]
Wikidata
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Interactions

RRAGA has been shown to interact with NOL8^[8] and RRAGC.^[9][10]