RSPH9

Radial spoke head protein 9 homolog is a protein that in humans is encoded by the RSPH9 gene.^[5][6]

RSPH9
Identifiers
Aliases	RSPH9, C6orf206, CILD12, MRPS18AL1, radial spoke head 9 homolog, radial spoke head component 9
External IDs	OMIM: 612648; MGI: 1922814; HomoloGene: 12606; GeneCards: RSPH9; OMA:RSPH9 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.1 Start 43,645,036 bp[1] End 43,672,600 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 C Start 46,432,961 bp[2] End 46,455,142 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bronchial epithelial cell mucosa of paranasal sinus right uterine tube olfactory zone of nasal mucosa nasal epithelium gonad left testis right testis epithelium of nasopharynx testicle Top expressed in spermatid spermatocyte olfactory epithelium Epithelium of choroid plexus seminiferous tubule seminal vesicula lateral recess utricle right kidney Region I of hippocampus proper More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm cell projection motile cilium cilium cytoskeleton axoneme 9+2 motile cilium radial spoke Biological process cilium movement involved in cell motility cilium movement motile cilium assembly axoneme assembly cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 221421 75564 Ensembl ENSG00000172426 ENSMUSG00000023966 UniProt Q9H1X1 Q9D9V4 RefSeq (mRNA) NM_001193341 NM_152732 NM_029338 RefSeq (protein) NP_001180270 NP_689945 NP_083614 Location (UCSC) Chr 6: 43.65 – 43.67 Mb Chr 17: 46.43 – 46.46 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes a protein thought to be a component of the radial spoke head in motile cilia and flagellawhich then releases antibodies .^[5]

Clinical significance

Mutation in this gene are associated with primary ciliary dyskinesia.^[6]