Relaxin/insulin-like family peptide receptor 3

Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor.^[5]

RXFP3
Identifiers
Aliases	RXFP3, GPCR135, RLN3R1, RXFPR3, SALPR, Relaxin/insulin-like family peptide receptor 3, relaxin/insulin like family peptide receptor 3, relaxin family peptide receptor 3
External IDs	OMIM: 609445; MGI: 2441827; HomoloGene: 9568; GeneCards: RXFP3; OMA:RXFP3 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p13.2 Start 33,936,386 bp[1] End 33,938,918 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 A1 Start 11,033,803 bp[2] End 11,038,077 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans right adrenal cortex left adrenal cortex prefrontal cortex superior frontal gyrus anterior pituitary Hypothalamus caudate nucleus substantia nigra head Top expressed in embryo dentate gyrus of hippocampal formation granule cell embryo hippocampus proper Hypothalamus visual cortex neural tube Mesencephalon neural layer of retina primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity galanin receptor activity G protein-coupled peptide receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process positive regulation of cytokinesis G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway signal transduction adenylate cyclase-modulating G protein-coupled receptor signaling pathway neuropeptide signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51289 239336 Ensembl ENSG00000182631 ENSG00000277069 ENSMUSG00000060735 UniProt Q9NSD7 Q8BGE9 RefSeq (mRNA) NM_016568 NM_178717 RefSeq (protein) NP_057652 NP_848832 Location (UCSC) Chr 5: 33.94 – 33.94 Mb Chr 15: 11.03 – 11.04 Mb PubMed search [3] [4]
Wikidata
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See also

• Relaxin receptor