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Revakinagene taroretcel

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Revakinagene taroretcel, sold under the brand name Encelto, is an allogeneic encapsulated cell-based gene therapy used for the treatment of macular telangiectasia type 2.[1][2] Revakinagene taroretcel is administered into the recipient's eye during a single surgical procedure.[3]

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Revakinagene taroretcel works by expressing recombinant human ciliary neurotrophic factor, which is a factor that may promote the survival and maintenance of the macular photoreceptors.[3]

Revakinagene taroretcel was approved for medical use in the United States in March 2025.[3][4]

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Medical uses

Revakinagene taroretcel is indicated for the treatment of adults with idiopathic macular telangiectasia type 2.[1][4]

Macular telangiectasia type 2 is a rare progressive disease of the macula (portion of the eye that process sharp central vision), leading to degeneration of the photoreceptors which are specialized light-detecting cells in the back of the eye.[3]

Society and culture

Revakinagene taroretcel was approved for medical use in the United States in March 2025.[4][5]

Names

Revakinagene taroretcel is the international nonproprietary name[6] and the United States Adopted Name.[7]

References

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