SASH1

SAM and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SASH1 gene.^[5][6][7]

SASH1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2EBP
Identifiers
Aliases	SASH1, SH3D6A, dJ323M4, dJ323M4.1, SAM and SH3 domain containing 1, DUH1, CAPOK
External IDs	OMIM: 607955; MGI: 1917347; HomoloGene: 69182; GeneCards: SASH1; OMA:SASH1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q24.3-q25.1 Start 148,272,304 bp[1] End 148,552,044 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A1 Start 8,597,983 bp[2] End 8,761,814 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in synovial joint external globus pallidus skin of hip subthalamic nucleus skin of thigh inferior ganglion of vagus nerve oral cavity pars reticulata Achilles tendon lateral nuclear group of thalamus Top expressed in stroma of bone marrow transitional epithelium of urinary bladder medial geniculate nucleus lateral geniculate nucleus substantia nigra suprachiasmatic nucleus ventral tegmental area medial dorsal nucleus lateral hypothalamus deep cerebellar nuclei More reference expression data BioGPS More reference expression data
Gene ontology Molecular function mitogen-activated protein kinase kinase kinase binding molecular adaptor activity protein C-terminus binding protein kinase binding Cellular component protein-containing complex Biological process positive regulation of endothelial cell migration positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of JUN kinase activity regulation of protein K63-linked ubiquitination positive regulation of p38MAPK cascade regulation of protein autoubiquitination protein polyubiquitination positive regulation of NIK/NF-kappaB signaling positive regulation of angiogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23328 70097 Ensembl ENSG00000111961 ENSMUSG00000015305 UniProt O94885 P59808 RefSeq (mRNA) NM_015278 NM_001346505 NM_001346506 NM_001346507 NM_001346508 NM_001346509 NM_175155 RefSeq (protein) NP_001333434 NP_001333435 NP_001333436 NP_001333437 NP_001333438 NP_056093 NP_780364 Location (UCSC) Chr 6: 148.27 – 148.55 Mb Chr 10: 8.6 – 8.76 Mb PubMed search [3] [4]
Wikidata
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