SAT2

This article is about the human gene. For the submarine communications cable, see SAT-2. For the SAT II tests, see SAT Subject Tests.

Diamine acetyltransferase 2 is an enzyme that in humans is encoded by the SAT2 gene.^[5][6][7] SAT2 maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate.^[8]

SAT2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2BEI, 2Q4V
Identifiers
Aliases	SAT2, Sspermidine/spermine N1-acetyltransferase family member 2, SSAT-2
External IDs	OMIM: 611463; MGI: 1916465; HomoloGene: 44215; GeneCards: SAT2; OMA:SAT2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 7,626,234 bp[1] End 7,627,876 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B3 Start 69,512,850 bp[2] End 69,514,696 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal cortex left adrenal cortex jejunal mucosa right lobe of liver mucosa of ileum duodenum human kidney left ovary right ovary anterior pituitary Top expressed in otolith organ utricle retinal pigment epithelium right kidney proximal tubule otic vesicle Rostral migratory stream internal carotid artery external carotid artery epithelium of lens More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity N-acetyltransferase activity acyltransferase activity diamine N-acetyltransferase activity protein binding identical protein binding spermidine binding Cellular component cytoplasm extracellular exosome Biological process putrescine acetylation spermine acetylation nor-spermidine metabolic process spermidine acetylation putrescine catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 112483 69215 Ensembl ENSG00000141504 ENSMUSG00000069835 UniProt Q96F10 Q6P8J2 RefSeq (mRNA) NM_133491 NM_001320845 NM_001320846 NM_001320847 NM_026991 NM_001356468 NM_001356469 RefSeq (protein) NP_001307774 NP_001307775 NP_001307776 NP_597998 NP_081267 NP_001343397 NP_001343398 Location (UCSC) Chr 17: 7.63 – 7.63 Mb Chr 11: 69.51 – 69.51 Mb PubMed search [3] [4]
Wikidata
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