SCN2B

Sodium channel subunit beta-2 is a protein that in humans is encoded by the SCN2B gene.^[5][6]

SCN2B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5FEB, 5FDY
Identifiers
Aliases	SCN2B, ATFB14, sodium voltage-gated channel beta subunit 2
External IDs	OMIM: 601327; MGI: 106921; HomoloGene: 3373; GeneCards: SCN2B; OMA:SCN2B - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.3 Start 118,162,806 bp[1] End 118,176,639 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 A5.2|9 24.84 cM Start 45,029,080 bp[2] End 45,041,368 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus lateral nuclear group of thalamus cerebellar cortex cerebellar hemisphere prefrontal cortex right hemisphere of cerebellum cerebellar vermis superior frontal gyrus primary visual cortex right frontal lobe Top expressed in lobe of cerebellum cerebellar vermis lateral geniculate nucleus olfactory tubercle superior colliculus medial geniculate nucleus habenula lateral septal nucleus lateral hypothalamus medial dorsal nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function voltage-gated sodium channel activity involved in cardiac muscle cell action potential sodium channel regulator activity sodium channel activity voltage-gated sodium channel activity voltage-gated ion channel activity Cellular component integral component of membrane voltage-gated sodium channel complex membrane Biological process chemical synaptic transmission nervous system development cardiac muscle cell action potential involved in contraction sodium ion transport sodium ion transmembrane transport regulation of sodium ion transmembrane transporter activity cardiac muscle contraction regulation of heart rate by cardiac conduction regulation of atrial cardiac muscle cell membrane depolarization membrane depolarization during cardiac muscle cell action potential regulation of ion transmembrane transport ion transport response to pyrethroid Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6327 72821 Ensembl ENSG00000149575 ENSMUSG00000070304 UniProt O60939 Q56A07 RefSeq (mRNA) NM_004588 NM_001014761 RefSeq (protein) NP_004579 NP_001014761 Location (UCSC) Chr 11: 118.16 – 118.18 Mb Chr 9: 45.03 – 45.04 Mb PubMed search [3] [4]
Wikidata
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See also

• Sodium channel