SCYL2

SCY1-like protein 2 is a protein that in humans is encoded by the SCYL2 gene.^[5][6]

SCYL2
Identifiers
Aliases	SCYL2, CVAK104, SCY1 like pseudokinase 2, AMCNACC, AMC4
External IDs	OMIM: 616365; MGI: 1289172; HomoloGene: 13349; GeneCards: SCYL2; OMA:SCYL2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q23.1 Start 100,267,140 bp[1] End 100,341,715 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 C2|10 45.05 cM Start 89,474,583 bp[2] End 89,522,147 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of sigmoid colon corpus epididymis secondary oocyte jejunal mucosa palpebral conjunctiva amniotic fluid oral cavity rectum tail of epididymis monocyte Top expressed in secondary oocyte zygote hand primary oocyte lumbar spinal ganglion tail of embryo superior cervical ganglion granulocyte genital tubercle endocardial cushion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ATP binding signaling receptor binding protein kinase activity protein binding Cellular component Golgi apparatus endosome membrane membrane cytoplasmic vesicle clathrin-coated vesicle cytoplasm endosome perinuclear region of cytoplasm Biological process receptor internalization involved in canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway protein phosphorylation endosome to lysosome transport positive regulation of clathrin-dependent endocytosis positive regulation of receptor internalization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55681 213326 Ensembl ENSG00000136021 ENSMUSG00000069539 UniProt Q6P3W7 Q8CFE4 RefSeq (mRNA) NM_017988 NM_001317784 NM_001330253 NM_001330254 NM_001330256 NM_198021 NM_001310704 NM_001358843 RefSeq (protein) NP_001304713 NP_001317182 NP_001317183 NP_001317185 NP_060458 NP_001297633 NP_932138 NP_001345772 Location (UCSC) Chr 12: 100.27 – 100.34 Mb Chr 10: 89.47 – 89.52 Mb PubMed search [3] [4]
Wikidata
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