SEC22A

Vesicle-trafficking protein SEC22a is a protein that in humans is encoded by the SEC22A gene.^[5][6][7]

SEC22A
Identifiers
Aliases	SEC22A, SEC22L2, SEC22 homolog A, vesicle trafficking protein
External IDs	OMIM: 612442; MGI: 2447876; HomoloGene: 8246; GeneCards: SEC22A; OMA:SEC22A - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q21.1 Start 123,201,927 bp[1] End 123,274,136 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 B3 Start 35,131,501 bp[2] End 35,184,288 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte Achilles tendon islet of Langerhans gonad left testis testicle right testis ventricular zone ganglionic eminence stromal cell of endometrium Top expressed in spermatocyte medullary collecting duct primary oocyte spermatid secondary oocyte renal corpuscle right kidney epithelium of lens zygote interventricular septum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SNAP receptor activity protein binding SNARE binding transporter activity Cellular component integral component of membrane endoplasmic reticulum membrane endoplasmic reticulum membrane SNARE complex Biological process protein transport vesicle-mediated transport vesicle fusion with Golgi apparatus exocytosis endoplasmic reticulum to Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26984 317717 Ensembl ENSG00000121542 ENSMUSG00000034473 UniProt Q96IW7 Q8BH47 RefSeq (mRNA) NM_012430 NM_133704 RefSeq (protein) NP_036562 NP_598465 Location (UCSC) Chr 3: 123.2 – 123.27 Mb Chr 16: 35.13 – 35.18 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene belongs to the member of the SEC22 family of vesicle trafficking proteins. This protein has similarity to rat SEC22 and may act in the early stages of the secretory pathway. There is evidence for the use of multiple poly A sites in this gene.^[7]