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SEC61B

Mammalian protein found in Homo sapiens From Wikipedia, the free encyclopedia

SEC61B
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Protein transport protein Sec61 subunit beta is a protein that in humans is encoded by the SEC61B gene.[5][6][7]

Quick Facts Available structures, PDB ...

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The Sec61 complex forms a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.[7]

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