SELENBP1

Selenium-binding protein 1 is a protein that in humans is encoded by the SELENBP1 gene.^[5][6]

SELENBP1
Identifiers
Aliases	SELENBP1, HEL-S-134P, LPSB, SBP56, SP56, hSBP, selenium binding protein 1, MTO, EHMTO
External IDs	OMIM: 604188; MGI: 104859; HomoloGene: 2930; GeneCards: SELENBP1; OMA:SELENBP1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q21.3 Start 151,364,304 bp[1] End 151,372,707 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 F2.1|3 40.74 cM Start 94,600,863 bp[2] End 94,611,720 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon rectum mucosa of sigmoid colon right uterine tube right lobe of thyroid gland right lobe of liver left lobe of thyroid gland body of stomach olfactory zone of nasal mucosa fundus Top expressed in liver renal cortex proximal tubule white adipose tissue right kidney human kidney right lung pharynx bone marrow left lung More reference expression data BioGPS More reference expression data
Gene ontology Molecular function selenium binding protein binding oxidoreductase activity methanethiol oxidase activity Cellular component cytoplasm cytosol nucleolus extracellular exosome membrane nucleus fibrillar center extracellular space Biological process protein transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8991 20342 Ensembl ENSG00000143416 ENSMUSG00000068877 UniProt Q13228 Q63836 RefSeq (mRNA) NM_001258288 NM_001258289 NM_003944 NM_032183 NM_019414 RefSeq (protein) NP_001245217 NP_001245218 NP_003935 NP_062287 Location (UCSC) Chr 1: 151.36 – 151.37 Mb Chr 3: 94.6 – 94.61 Mb PubMed search [3] [4]
Wikidata
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This gene product belongs to the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. It has been proposed that the effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins. The exact function of this gene is not known.^[6]

Interactions

SELENBP1 has been shown to interact with USP33.^[7]