SEMA3C

Semaphorin-3C is a protein that in humans is encoded by the SEMA3C gene.^[5][6][7]

SEMA3C
Identifiers
Aliases	SEMA3C, SEMAE, SemE, semaphorin 3C
External IDs	OMIM: 602645; MGI: 107557; HomoloGene: 36201; GeneCards: SEMA3C; OMA:SEMA3C - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.11 Start 80,742,538 bp[1] End 80,922,359 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 A3 Start 17,779,279 bp[2] End 17,935,266 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lactiferous duct synovial joint Achilles tendon cartilage tissue germinal epithelium skin of hip vena cava synovial membrane tail of epididymis biceps brachii Top expressed in retinal pigment epithelium right lung lobe submandibular gland ankle medullary collecting duct left colon calvaria skin of external ear vas deferens seminal vesicula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function semaphorin receptor binding neuropilin binding chemorepellent activity Cellular component extracellular region extracellular exosome extracellular space integral component of plasma membrane Biological process somitogenesis cell differentiation limb bud formation outflow tract morphogenesis post-embryonic development nervous system development axon guidance multicellular organism development heart development blood vessel remodeling pulmonary myocardium development immune response neural tube development dichotomous subdivision of terminal units involved in salivary gland branching cardiac right ventricle morphogenesis neural crest cell migration negative chemotaxis outflow tract septum morphogenesis semaphorin-plexin signaling pathway cardiac endothelial to mesenchymal transition positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis positive regulation of cell migration negative regulation of axon extension involved in axon guidance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10512 20348 Ensembl ENSG00000075223 ENSMUSG00000028780 UniProt Q99985 Q62181 RefSeq (mRNA) NM_006379 NM_001350120 NM_001350121 NM_013657 RefSeq (protein) NP_006370 NP_001337049 NP_001337050 NP_038685 Location (UCSC) Chr 7: 80.74 – 80.92 Mb Chr 5: 17.78 – 17.94 Mb PubMed search [3] [4]
Wikidata
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