SEMA4F

Semaphorin-4F is a protein that in humans is encoded by the SEMA4F gene.^[5][6]

SEMA4F
Identifiers
Aliases	SEMA4F, M-SEMA, PRO2353, S4F, SEMAM, SEMAW, m-Sema-M, ssemaphorin 4F
External IDs	OMIM: 603706; MGI: 1340055; HomoloGene: 3147; GeneCards: SEMA4F; OMA:SEMA4F - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p13.1 Start 74,654,228 bp[1] End 74,683,853 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 C3|6 35.94 cM Start 82,888,866 bp[2] End 82,916,750 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell middle temporal gyrus prefrontal cortex gonad testicle superior frontal gyrus sural nerve right frontal lobe postcentral gyrus Brodmann area 23 Top expressed in trigeminal ganglion substantia nigra ventromedial nucleus lumbar spinal ganglion perirhinal cortex entorhinal cortex condyle CA3 field primary motor cortex arcuate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function neuropilin binding semaphorin receptor binding chemorepellent activity Cellular component integral component of membrane postsynaptic membrane membrane plasma membrane synapse integral component of plasma membrane endoplasmic reticulum extracellular space postsynaptic density cell junction dendrite cell projection perikaryon Biological process cell differentiation cell-cell signaling nervous system development axon guidance multicellular organism development negative regulation of axon extension retinal ganglion cell axon guidance negative chemotaxis neural crest cell migration positive regulation of cell migration negative regulation of axon extension involved in axon guidance semaphorin-plexin signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10505 20355 Ensembl ENSG00000135622 ENSMUSG00000000627 UniProt O95754 Q9Z123 RefSeq (mRNA) NM_001271661 NM_001271662 NM_004263 NM_001113481 NM_011350 NM_001308374 RefSeq (protein) NP_001258590 NP_001258591 NP_004254 NP_001295303 NP_035480 Location (UCSC) Chr 2: 74.65 – 74.68 Mb Chr 6: 82.89 – 82.92 Mb PubMed search [3] [4]
Wikidata
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