SERBP1

Not to be confused with srebp1.

Plasminogen activator inhibitor 1 RNA-binding protein (serbp1) is a protein that in humans is encoded by the SERBP1 gene.^[5][6][7]

SERBP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4V6X
Identifiers
Aliases	SERBP1, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1, CGI-55, SERPINE1 mRNA binding protein 1
External IDs	OMIM: 607378; MGI: 1914120; HomoloGene: 134277; GeneCards: SERBP1; OMA:SERBP1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p31.3 Start 67,407,810 bp[1] End 67,430,415 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 C1 Start 67,215,160 bp[2] End 67,274,720 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Skeletal muscle tissue of biceps brachii Achilles tendon Skeletal muscle tissue of rectus abdominis mucosa of sigmoid colon skin of thigh trabecular bone parietal pleura vulva triceps brachii muscle ventricular zone Top expressed in primitive streak tail of embryo abdominal wall condyle Rostral migratory stream medullary collecting duct hair follicle renal corpuscle endothelial cell of lymphatic vessel otic placode More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding mRNA 3'-UTR binding RNA binding cadherin binding SUMO binding Cellular component perinuclear region of cytoplasm plasma membrane extracellular exosome membrane cytosol nucleus cytoplasm Biological process regulation of apoptotic process regulation of mRNA stability PML body organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26135 66870 Ensembl ENSG00000142864 ENSMUSG00000036371 UniProt Q8NC51 Q9CY58 RefSeq (mRNA) NM_015640 NM_001018067 NM_001018068 NM_001018069 NM_001113564 NM_001113565 NM_001113566 NM_025814 RefSeq (protein) NP_001018077 NP_001018078 NP_001018079 NP_056455 NP_001107036 NP_001107037 NP_001107038 NP_080090 Location (UCSC) Chr 1: 67.41 – 67.43 Mb Chr 6: 67.22 – 67.27 Mb PubMed search [3] [4]
Wikidata
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Interactions

SERBP1 has been shown to interact with CHD3.^[8][9]