SERTAD1

SERTA domain-containing protein 1 is a protein that in humans is encoded by the SERTAD1 gene.^[5][6][7]

SERTAD1
Identifiers
Aliases	SERTAD1, SEI1, TRIP-Br1, SERTA domain containing 1, TRIPBR1
External IDs	OMIM: 617850; MGI: 1913438; HomoloGene: 8365; GeneCards: SERTAD1; OMA:SERTAD1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.2 Start 40,421,589 bp[1] End 40,425,992 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 A3 Start 27,186,335 bp[2] End 27,189,741 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in vena cava amniotic fluid lower lobe of lung mucosa of ileum saphenous vein trachea mucosa of pharynx tibialis anterior muscle pancreatic epithelial cell gastric mucosa Top expressed in granulocyte intestinal villus ascending aorta aortic valve sciatic nerve lip gastric mucosa mucous cell of stomach endothelial cell of lymphatic vessel epithelium of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm nucleus Biological process positive regulation of transcription, DNA-templated positive regulation of cell population proliferation positive regulation of transcription by RNA polymerase II transcription, DNA-templated regulation of cyclin-dependent protein serine/threonine kinase activity regulation of transcription, DNA-templated negative regulation of cell growth Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29950 55942 Ensembl ENSG00000197019 ENSMUSG00000008384 UniProt Q9UHV2 Q53GC0 Q9JL10 RefSeq (mRNA) NM_013376 NM_018820 RefSeq (protein) NP_037508 NP_037508.2 NP_061290 Location (UCSC) Chr 19: 40.42 – 40.43 Mb Chr 7: 27.19 – 27.19 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

SERTAD1 has been shown to interact with:

• CREB-binding protein,^[8]
• Cyclin-dependent kinase 4,^[6][9] and
• P16.^[6][9]