SFRS4

Splicing factor, arginine/serine-rich 4 is a protein that in humans is encoded by the SFRS4 gene.^[5][6]

SRSF4
Identifiers
Aliases	SRSF4, SFRS4, SRP75, serine/arginine-rich splicing factor 4, serine and arginine rich splicing factor 4
External IDs	OMIM: 601940; MGI: 1890577; HomoloGene: 25624; GeneCards: SRSF4; OMA:SRSF4 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p35.3 Start 29,147,743 bp[1] End 29,181,900 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D2.3 Start 131,873,617 bp[2] End 131,901,706 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve middle frontal gyrus paraflocculus of cerebellum ventricular zone body of uterus canal of the cervix gastric mucosa muscle layer of sigmoid colon left ovary right ovary Top expressed in neural layer of retina ventricular zone ascending aorta aortic valve primitive streak ganglionic eminence somite mandibular prominence maxillary prominence retinal pigment epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function sequence-specific mRNA binding nucleic acid binding protein binding RNA binding nucleotide binding Cellular component nucleus nucleoplasm nuclear speck Biological process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing negative regulation of mRNA splicing, via spliceosome mRNA 3'-end processing mRNA export from nucleus RNA splicing RNA export from nucleus response to insulin regulation of alternative mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6429 57317 Ensembl ENSG00000116350 ENSMUSG00000028911 UniProt Q08170 Q8VE97 RefSeq (mRNA) NM_005626 NM_020587 RefSeq (protein) NP_005617 n/a Location (UCSC) Chr 1: 29.15 – 29.18 Mb Chr 4: 131.87 – 131.9 Mb PubMed search [3] [4]
Wikidata
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Interactions

SFRS4 has been shown to interact with Pinin.^[7]