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SGK3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

SGK3
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Serine/threonine-protein kinase Sgk3 is an enzyme that in humans is encoded by the SGK3 gene.[5][6][7]

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Function

This gene is a member of the serine/threonine protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[7]

In melanocytic cells SGK3 gene expression may be regulated by MITF.[8]

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Interactions

SGK3 has been shown to interact with GSK3B.[9]

References

Further reading

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