SHCBP1

SHC SH2 domain-binding protein 1 is a protein that in humans is encoded by the SHCBP1 gene.^[5][6]

SHCBP1
Identifiers
Aliases	SHCBP1, PAL, SHC binding and spindle associated 1
External IDs	OMIM: 611027; MGI: 1338802; HomoloGene: 32123; GeneCards: SHCBP1; OMA:SHCBP1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q11.2 Start 46,578,591 bp[1] End 46,621,379 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 A1.1 Start 4,785,976 bp[2] End 4,829,567 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte ventricular zone bone marrow gonad ganglionic eminence trabecular bone stromal cell of endometrium bone marrow cell appendix testicle Top expressed in otic placode otic vesicle saccule primitive streak maxillary prominence mandibular prominence abdominal wall condyle vas deferens dermis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SH2 domain binding protein binding Cellular component cytoskeleton cytoplasm spindle midbody Biological process regulation of neural precursor cell proliferation fibroblast growth factor receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79801 20419 Ensembl ENSG00000171241 ENSMUSG00000022322 UniProt Q8NEM2 Q9Z179 RefSeq (mRNA) NM_024745 NM_001324318 NM_001324319 NM_011369 RefSeq (protein) NP_001311247 NP_001311248 NP_079021 NP_035499 Location (UCSC) Chr 16: 46.58 – 46.62 Mb Chr 8: 4.79 – 4.83 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

SHCBP1 has been shown to interact with SHC1.^[5]