SIGLEC5

Sialic acid-binding Ig-like lectin 5 is a protein that in humans is encoded by the SIGLEC5 gene.^[3][4] SIGLEC5 has also been designated CD170 (cluster of differentiation 170).

SIGLEC5
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2ZG1, 2ZG2, 2ZG3
Identifiers
Aliases	SIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5, sialic acid binding Ig like lectin 5
External IDs	OMIM: 604200; HomoloGene: 55783; GeneCards: SIGLEC5; OMA:SIGLEC5 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.41 Start 51,610,960 bp[1] End 51,630,401 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood bone marrow bone marrow cells granulocyte monocyte appendix lymph node right lung spleen duodenum n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function carbohydrate binding protein binding Cellular component integral component of membrane membrane plasma membrane secretory granule membrane tertiary granule membrane ficolin-1-rich granule membrane Biological process cell adhesion neutrophil degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8778 n/a Ensembl ENSG00000268500 n/a UniProt O15389 n/a RefSeq (mRNA) NM_003830 NM_001384708 NM_001384709 n/a RefSeq (protein) NP_003821 n/a Location (UCSC) Chr 19: 51.61 – 51.63 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human