SIGLEC7

Sialic acid-binding Ig-like lectin 7 is a protein that in humans is encoded by the SIGLEC7 gene.^[5][6] SIGLEC7 has also been designated as CD328 (cluster of differentiation 328).

SIGLEC7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1NKO, 1O7S, 1O7V, 2DF3, 2G5R, 2HRL
Identifiers
Aliases	SIGLEC7, AIRM1, CD328, CDw328, D-siglec, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2, p75, p75/AIRM1, sialic acid binding Ig like lectin 7, AIRM-1
External IDs	OMIM: 604410; MGI: 1932475; HomoloGene: 130668; GeneCards: SIGLEC7; OMA:SIGLEC7 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.41 Start 51,142,299 bp[1] End 51,153,526 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 B3|7 Start 43,300,494 bp[2] End 43,309,585 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte blood spleen gonad testicle appendix amniotic fluid lymph node right adrenal cortex Top expressed in granulocyte zygote secondary oocyte spleen blood embryo embryo right kidney bone marrow primary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function carbohydrate binding signaling receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process cell adhesion regulation of immune response signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27036 83382 Ensembl ENSG00000168995 ENSMUSG00000030474 UniProt Q9Y286 Q91Y57 RefSeq (mRNA) NM_001277201 NM_014385 NM_016543 NM_031181 RefSeq (protein) NP_001264130 NP_055200 NP_057627 NP_112458 Location (UCSC) Chr 19: 51.14 – 51.15 Mb Chr 7: 43.3 – 43.31 Mb PubMed search [3] [4]
Wikidata
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