SNF1LK2

Serine/threonine-protein kinase SIK2 is an enzyme that in humans is encoded by the SIK2 gene.^[5][6]

SIK2
Identifiers
Aliases	SIK2, LOH11CR1I, QIK, SNF1LK2, SIK-2, salt inducible kinase 2
External IDs	OMIM: 608973; MGI: 2445031; HomoloGene: 22875; GeneCards: SIK2; OMA:SIK2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.1 Start 111,602,449 bp[1] End 111,730,855 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A5.3 Start 50,804,101 bp[2] End 50,920,373 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Epithelium of choroid plexus cardia germinal epithelium adipose tissue lower lobe of lung hair follicle subcutaneous adipose tissue stromal cell of endometrium Skeletal muscle tissue of biceps brachii synovial joint Top expressed in brown adipose tissue otic vesicle white adipose tissue mammary gland subcutaneous adipose tissue ascending aorta muscle of thigh neural layer of retina genital tubercle aortic valve More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding magnesium ion binding metal ion binding kinase activity Cellular component cytoplasm nucleus nucleotide-activated protein kinase complex Biological process protein autophosphorylation protein phosphorylation intracellular signal transduction phosphorylation regulation of insulin receptor signaling pathway cellular response to hormone stimulus negative regulation of TOR signaling cellular response to glucose starvation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23235 235344 Ensembl ENSG00000170145 ENSMUSG00000037112 UniProt Q9H0K1 Q8CFH6 RefSeq (mRNA) NM_015191 NM_178710 RefSeq (protein) NP_056006 NP_848825 NP_001391943 NP_001391944 Location (UCSC) Chr 11: 111.6 – 111.73 Mb Chr 9: 50.8 – 50.92 Mb PubMed search [3] [4]
Wikidata
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Interactions

SNF1LK2 has been shown to interact with CRTC2.^[7]