SLC38A5

Solute carrier family 38 member 5 is a protein that in humans is encoded by the SLC38A5 gene. ^[5]

SLC38A5
Identifiers
Aliases	SLC38A5, JM24, SN2, SNAT5, pp7194, solute carrier family 38 member 5
External IDs	OMIM: 300649; MGI: 2148066; HomoloGene: 24917; GeneCards: SLC38A5; OMA:SLC38A5 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.23 Start 48,458,537 bp[1] End 48,470,260 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A1.1 Start 8,137,372 bp[2] End 8,146,418 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas bone marrow cell stromal cell of endometrium upper lobe of left lung C1 segment mucosa of transverse colon left lobe of thyroid gland ganglionic eminence right lobe of thyroid gland right frontal lobe Top expressed in fetal liver hematopoietic progenitor cell cumulus cell tibiofemoral joint lumbar subsegment of spinal cord left lung lobe blood pyloric antrum Ileal epithelium perirhinal cortex medial ganglionic eminence More reference expression data BioGPS n/a
Gene ontology Molecular function glycine transmembrane transporter activity amino acid transmembrane transporter activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process amino acid transport glycine transport amino acid transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 92745 209837 Ensembl ENSG00000017483 ENSMUSG00000031170 UniProt Q8WUX1 Q3U1J0 RefSeq (mRNA) NM_033518 NM_172479 RefSeq (protein) NP_277053 NP_766067 Location (UCSC) Chr X: 48.46 – 48.47 Mb Chr X: 8.14 – 8.15 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined.