SLC6A14

Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (SLC6A14) is a protein that in humans is encoded by the SLC6A14 gene.^[5][6]

SLC6A14
Identifiers
Aliases	SLC6A14, BMIQ11, solute carrier family 6 member 14
External IDs	OMIM: 300444; MGI: 1890216; HomoloGene: 38290; GeneCards: SLC6A14; OMA:SLC6A14 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq23 Start 116,436,606 bp[1] End 116,461,458 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A2 Start 21,581,135 bp[2] End 21,608,594 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva nasal epithelium mucosa of paranasal sinus epithelium of bronchus lower lobe of lung parotid gland bronchial epithelial cell amniotic fluid epithelium of nasopharynx olfactory zone of nasal mucosa Top expressed in left colon conjunctival fornix left lung lobe right lung vestibular sensory epithelium right lung lobe skin of external ear seminal vesicula olfactory epithelium cornea More reference expression data BioGPS More reference expression data
Gene ontology Molecular function symporter activity amino acid transmembrane transporter activity neurotransmitter:sodium symporter activity transporter activity Cellular component integral component of plasma membrane membrane brush border membrane vesicle extracellular exosome integral component of membrane plasma membrane Biological process neurotransmitter transport amino acid transport cellular amino acid metabolic process response to toxic substance transmembrane transport amino acid transmembrane transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11254 56774 Ensembl ENSG00000268104 ENSMUSG00000031089 UniProt Q9UN76 Q9JMA9 RefSeq (mRNA) NM_007231 NM_020049 RefSeq (protein) NP_009162 NP_064433 Location (UCSC) Chr X: 116.44 – 116.46 Mb Chr X: 21.58 – 21.61 Mb PubMed search [3] [4]
Wikidata
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Function

SLC6A14 is a member of the Na⁺- and Cl⁻-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids in an Na⁺- and Cl⁻-dependent manner.[supplied by OMIM]^[6]