SLIT1

Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene.^[5][6][7]

SLIT1
Identifiers
Aliases	SLIT1, MEGF4, SLIL1, SLIT-1, SLIT3, slit guidance ligand 1
External IDs	OMIM: 603742; MGI: 1315203; HomoloGene: 2302; GeneCards: SLIT1; OMA:SLIT1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q24.1 Start 96,998,038 bp[1] End 97,185,959 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C3 Start 41,588,696 bp[2] End 41,732,104 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus orbitofrontal cortex Region I of hippocampus proper Brodmann area 10 Brodmann area 23 Brodmann area 46 entorhinal cortex superior frontal gyrus pancreatic ductal cell frontal pole Top expressed in dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus urethra male urethra hippocampus proper stellate reticulum enamel knot ventricular zone Rostral migratory stream More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding Roundabout binding heparin binding Cellular component extracellular region extracellular space intracellular anatomical structure Biological process chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration cell differentiation neuron projection morphogenesis dorsal/ventral axon guidance negative chemotaxis axonogenesis negative regulation of synapse assembly nervous system development telencephalon cell migration multicellular organism development forebrain morphogenesis tangential migration from the subventricular zone to the olfactory bulb olfactory bulb development motor neuron axon guidance axon extension involved in axon guidance retinal ganglion cell axon guidance axon guidance nuclear migration Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6585 20562 Ensembl ENSG00000187122 ENSMUSG00000025020 UniProt O75093 Q80TR4 RefSeq (mRNA) NM_003061 NM_015748 RefSeq (protein) NP_003052 NP_056563 Location (UCSC) Chr 10: 97 – 97.19 Mb Chr 19: 41.59 – 41.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse