SMG7

Protein SMG7 is a protein that in humans is encoded by the SMG7 gene.^[5][6][7][8]

SMG7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1YA0
Identifiers
Aliases	SMG7, C1orf16, EST1C, SGA56M, nonsense mediated mRNA decay factor, SMG7 nonsense mediated mRNA decay factor
External IDs	OMIM: 610964; MGI: 2682334; HomoloGene: 32235; GeneCards: SMG7; OMA:SMG7 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q25.3 Start 183,472,216 bp[1] End 183,598,246 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 G3 Start 152,712,746 bp[2] End 152,778,397 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in internal globus pallidus tendon of biceps brachii right uterine tube right testis left testis islet of Langerhans epithelium of colon ganglionic eminence postcentral gyrus cerebellar cortex Top expressed in tail of embryo genital tubercle ascending aorta aortic valve zygote blood hand cumulus cell mesenteric lymph nodes interventricular septum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein phosphatase 2A binding protein binding telomeric DNA binding ribonuclease activity ribonucleoprotein complex binding telomerase RNA binding Cellular component cytoplasm intermediate filament cytoskeleton nucleus telomerase holoenzyme complex cytosol Biological process regulation of dephosphorylation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay mRNA export from nucleus telomere maintenance via telomerase regulation of RNA stability RNA phosphodiester bond hydrolysis regulation of telomere maintenance via telomerase Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9887 226517 Ensembl ENSG00000116698 ENSMUSG00000042772 UniProt Q92540 Q5RJH6 RefSeq (mRNA) NM_001174061 NM_014837 NM_173156 NM_201568 NM_201569 NM_001331007 NM_001350219 NM_001350220 NM_001350221 NM_001350222 NM_001375584 NM_001375585 NM_001005507 NM_001160256 NM_001160257 NM_001359257 RefSeq (protein) NP_001167532 NP_001317936 NP_775179 NP_963862 NP_963863 NP_001337148 NP_001337149 NP_001337150 NP_001337151 NP_001362513 NP_001362514 NP_001005507 NP_001153728 NP_001153729 NP_001346186 Location (UCSC) Chr 1: 183.47 – 183.6 Mb Chr 1: 152.71 – 152.78 Mb PubMed search [3] [4]
Wikidata
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