SORD

"SORD (gene)" redirects here. For other uses, see Sord.

Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene.^[5][6]

SORD
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1PL8, 1PL6, 1PL7
Identifiers
Aliases	SORD, HEL-S-95n, SORD1, sorbitol dehydrogenase, XDH, RDH, SDH, SORDD
External IDs	OMIM: 182500; MGI: 98266; HomoloGene: 56080; GeneCards: SORD; OMA:SORD - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q21.1 Start 45,023,147 bp[1] End 45,077,185 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 E5|2 60.59 cM Start 122,065,230 bp[2] End 122,095,821 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland right lobe of liver olfactory zone of nasal mucosa prostate right adrenal cortex left adrenal gland left adrenal cortex islet of Langerhans ventricular zone Top expressed in seminiferous tubule spermatid right kidney spermatocyte left lobe of liver human kidney seminal vesicula morula blastocyst myocardium of ventricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function NAD binding zinc ion binding metal ion binding L-iditol 2-dehydrogenase activity oxidoreductase activity D-xylulose reductase activity carbohydrate binding identical protein binding (R,R)-butanediol dehydrogenase activity ribitol 2-dehydrogenase activity Cellular component cytosol cell projection membrane mitochondrial membranes cilium mitochondrion motile cilium extracellular exosome extracellular space Biological process flagellated sperm motility response to cadmium ion response to copper ion sorbitol catabolic process fructose biosynthetic process glucuronate catabolic process to xylulose 5-phosphate response to osmotic stress L-xylitol metabolic process response to nutrient levels glucose metabolic process L-xylitol catabolic process response to hormone sorbitol metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6652 20322 Ensembl ENSG00000140263 ENSMUSG00000027227 UniProt Q00796 Q64442 RefSeq (mRNA) NM_003104 NM_146126 RefSeq (protein) NP_003095 NP_666238 Location (UCSC) Chr 15: 45.02 – 45.08 Mb Chr 2: 122.07 – 122.1 Mb PubMed search [3] [4]
Wikidata
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