SOX15

Protein SOX-15 is a protein that in humans is encoded by the SOX15 gene.^[5][6][7]

SOX15
Identifiers
Aliases	SOX15, SOX20, SOX26, SOX27, SRY-box 15, SRY-box transcription factor 15
External IDs	OMIM: 601297; MGI: 98363; HomoloGene: 74586; GeneCards: SOX15; OMA:SOX15 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 7,588,178 bp[1] End 7,590,094 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B3|11 42.86 cM Start 69,546,140 bp[2] End 69,547,553 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte skin of abdomen skin of leg mucosa of pharynx vagina right hemisphere of cerebellum olfactory zone of nasal mucosa gonad epithelium of esophagus Top expressed in morula blastocyst morula corneal stroma transitional epithelium of urinary bladder lip secondary oocyte zygote esophagus entorhinal cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding DNA-binding transcription factor activity chromatin binding protein binding protein heterodimerization activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific Cellular component cytoplasm nucleus Biological process positive regulation of myoblast proliferation cell differentiation male gonad development regulation of transcription, DNA-templated positive regulation of satellite cell activation involved in skeletal muscle regeneration negative regulation of striated muscle tissue development regulation of transcription by RNA polymerase II positive regulation of G0 to G1 transition negative regulation of transcription by RNA polymerase II chromatin organization myoblast development skeletal muscle tissue regeneration positive regulation of transcription by RNA polymerase II central nervous system development neuron differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6665 20670 Ensembl ENSG00000129194 ENSMUSG00000041287 UniProt O60248 P43267 RefSeq (mRNA) NM_006942 NM_009235 RefSeq (protein) NP_008873 NP_033261 Location (UCSC) Chr 17: 7.59 – 7.59 Mb Chr 11: 69.55 – 69.55 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.^[7]

See also

• SOX genes