SOX2OT

SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA, containing at least 5 exons. The SOX2 gene, an important regulator of neurogenesis, lies within one of the introns of SOX2OT.^[3] SOX2OT and SOX2DOT (an isoform of SOXOT transcribed from a distal highly conserved element) are expressed in zones of neurogenesis within the brain. It is associated with central nervous system structures in zebrafish and chicken embryonic brains, and is dynamically regulated during embryogenesis.^[4] SOX2OT may play a role in vertebrate development.^[4]

SOX2-OT
Identifiers
Aliases	SOX2-OT, NCRNA00043, SOX2 overlapping transcript
External IDs	OMIM: 616338; GeneCards: SOX2-OT; OMA:SOX2-OT - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q26.33 Start 180,989,762 bp[1] End 181,836,880 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum subthalamic nucleus inferior ganglion of vagus nerve external globus pallidus pars reticulata C1 segment medulla oblongata pons superior vestibular nucleus pars compacta n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 347689 n/a Ensembl ENSG00000242808 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 3: 180.99 – 181.84 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

• Long noncoding RNA