SPIN1

Spindlin-1 is a protein that in humans is encoded by the SPIN1 gene.^[5][6]

SPIN1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2NS2, 4H75, 4MZF, 4MZG, 4MZH
Identifiers
Aliases	SPIN1, SPIN, TDRD24, spindlin 1
External IDs	OMIM: 609936; MGI: 109242; HomoloGene: 55983; GeneCards: SPIN1; OMA:SPIN1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q22.1 Start 88,388,430 bp[1] End 88,478,694 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13 A5|13 26.04 cM Start 51,254,916 bp[2] End 51,306,582 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in postcentral gyrus caput epididymis corpus epididymis superior vestibular nucleus middle temporal gyrus entorhinal cortex Brodmann area 23 seminal vesicula renal medulla superior frontal gyrus Top expressed in primary oocyte secondary oocyte zygote fossa condyle motor neuron Paneth cell substantia nigra Rostral migratory stream facial motor nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function methylated histone binding protein binding Cellular component nucleus spindle nucleolus nucleoplasm cytosol nuclear membrane Biological process multicellular organism development Wnt signaling pathway cell cycle meiosis rRNA transcription gamete generation positive regulation of Wnt signaling pathway positive regulation of transcription, DNA-templated chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10927 20729 Ensembl ENSG00000106723 ENSMUSG00000021395 UniProt Q9Y657 Q61142 RefSeq (mRNA) NM_006717 NM_001283028 NM_001283029 NM_001283030 NM_011462 NM_146043 RefSeq (protein) NP_006708 NP_001269957 NP_001269958 NP_001269959 NP_035592 NP_666155 Location (UCSC) Chr 9: 88.39 – 88.48 Mb Chr 13: 51.25 – 51.31 Mb PubMed search [3] [4]
Wikidata
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