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SPRY4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

SPRY4
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Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene.[5][6]

Quick Facts Available structures, PDB ...
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Function

SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002).[6]

Interactions

SPRY4 has been shown to interact with TESK1.[7]

See also

References

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Further reading

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