SRGAP3

SLIT-ROBO Rho GTPase-activating protein 3 is an enzyme that in humans is encoded by the SRGAP3 gene.^[5][6]

SRGAP3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1AM4, 1GRN, 1OW3, 1RGP, 1TX4, 2NGR
Identifiers
Aliases	SRGAP3, ARHGAP14, MEGAP, SRGAP2, WRP, SLIT-ROBO Rho GTPase activating protein 3
External IDs	OMIM: 606525; MGI: 2152938; HomoloGene: 56686; GeneCards: SRGAP3; OMA:SRGAP3 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p25.3 Start 8,980,591 bp[1] End 9,363,053 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 E3 Start 112,694,932 bp[2] End 112,924,227 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus Brodmann area 23 paraflocculus of cerebellum Brodmann area 10 frontal pole right uterine tube endothelial cell Region I of hippocampus proper Brodmann area 46 postcentral gyrus Top expressed in subiculum pontine nuclei superior colliculus cingulate gyrus piriform cortex dentate gyrus cerebellar vermis lateral septal nucleus hippocampus proper anterior amygdaloid area More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding GTPase activator activity Cellular component cytoplasm cytosol Biological process negative regulation of cell migration regulation of small GTPase mediated signal transduction signal transduction positive regulation of GTPase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9901 259302 Ensembl ENSG00000196220 ENSMUSG00000030257 UniProt O43295 Q812A2 RefSeq (mRNA) NM_001033116 NM_001033117 NM_014850 NM_080448 NM_153070 RefSeq (protein) NP_001028289 NP_055665 NP_536696 Location (UCSC) Chr 3: 8.98 – 9.36 Mb Chr 6: 112.69 – 112.92 Mb PubMed search [3] [4]
Wikidata
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