SSC4D

Scavenger receptor cysteine rich family member with 4 domains is a protein that in humans is encoded by the SSC4D gene. ^[5]

SSC4D
Identifiers
Aliases	SSC4D, S4D-SRCRB, SRCRB-S4D, SRCRB4D, scavenger receptor cysteine rich family member with 4 domains
External IDs	OMIM: 607639; MGI: 1924709; HomoloGene: 34137; GeneCards: SSC4D; OMA:SSC4D - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q11.23 Start 76,389,334 bp[1] End 76,409,697 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 135,989,065 bp[2] End 136,003,385 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland testicle gonad middle temporal gyrus deltoid muscle tibialis anterior muscle thalamus pons internal globus pallidus pars compacta Top expressed in vestibular sensory epithelium otolith organ utricle granulocyte otic vesicle primary oocyte zygote stria vascularis secondary oocyte vestibular membrane of cochlear duct More reference expression data BioGPS n/a
Gene ontology Molecular function scavenger receptor activity Cellular component membrane extracellular region external side of plasma membrane Biological process receptor-mediated endocytosis vesicle-mediated transport endocytosis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 136853 109267 Ensembl ENSG00000146700 ENSMUSG00000029699 UniProt Q8WTU2 A1L0T3 RefSeq (mRNA) NM_080744 NM_001160366 RefSeq (protein) NP_542782 NP_001153838 Location (UCSC) Chr 7: 76.39 – 76.41 Mb Chr 5: 135.99 – 136 Mb PubMed search [3] [4]
Wikidata
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Function

The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.