STATH

Statherin is a protein in humans that is encoded by the STATH gene.^[3][4] It prevents the precipitation of calcium phosphate in saliva, maintaining a high calcium level in saliva available for remineralisation of tooth enamel and high phosphate levels for buffering.^[5]

STATH
Identifiers
Aliases	STATH, STR, statherin
External IDs	OMIM: 184470; HomoloGene: 88673; GeneCards: STATH; OMA:STATH - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q13.3 Start 69,995,966 bp[1] End 70,002,570 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory zone of nasal mucosa salivary gland minor salivary glands tonsil testicle placenta bone marrow bone marrow cells gonad skeletal muscle tissue n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function extracellular matrix constituent, lubricant activity hydroxyapatite binding structural constituent of tooth enamel protein binding Cellular component extracellular region Biological process defense response to bacterium negative regulation of bone mineralization ossification saliva secretion biomineral tissue development regulation of bone mineralization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6779 n/a Ensembl ENSG00000282891 ENSG00000126549 n/a UniProt P02808 n/a RefSeq (mRNA) NM_003154 NM_001009181 n/a RefSeq (protein) NP_001009181 NP_003145 n/a Location (UCSC) Chr 4: 70 – 70 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human