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STK10

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

STK10
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Serine/threonine-protein kinase 10 is an enzyme that in humans is encoded by the STK10 gene.[5][6]

Quick Facts Available structures, PDB ...

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.[6]

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