STMN2

Stathmin-2 is a protein that in humans is encoded by the STMN2 gene.^[5][6][7]

STMN2
Identifiers
Aliases	STMN2, SCG10, SCGN10, stathmin 2
External IDs	OMIM: 600621; MGI: 98241; HomoloGene: 5102; GeneCards: STMN2; OMA:STMN2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q21.13 Start 79,611,117 bp[1] End 79,666,158 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 A1|3 2.15 cM Start 8,574,420 bp[2] End 8,626,666 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pons cerebellar vermis spinal ganglia lateral nuclear group of thalamus ganglionic eminence pars compacta superior vestibular nucleus frontal pole cerebellar hemisphere paraflocculus of cerebellum Top expressed in superior cervical ganglion barrel cortex anterior horn of spinal cord lobe of cerebellum medial dorsal nucleus facial motor nucleus cerebellar vermis cingulate gyrus medulla oblongata dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium-dependent protein binding tubulin binding protein binding Cellular component cytoplasm vesicle endosome Golgi apparatus cell projection membrane growth cone axon soma perinuclear region of cytoplasm neuron projection lamellipodium Biological process cellular response to nerve growth factor stimulus negative regulation of neuron projection development negative regulation of microtubule polymerization negative regulation of microtubule depolymerization regulation of microtubule polymerization or depolymerization positive regulation of neuron projection development positive regulation of microtubule depolymerization microtubule depolymerization neuron projection development regulation of cytoskeleton organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11075 20257 Ensembl ENSG00000104435 ENSMUSG00000027500 UniProt Q93045 P55821 RefSeq (mRNA) NM_001199214 NM_007029 NM_025285 RefSeq (protein) NP_001186143 NP_008960 NP_079561 Location (UCSC) Chr 8: 79.61 – 79.67 Mb Chr 3: 8.57 – 8.63 Mb PubMed search [3] [4]
Wikidata
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Function

Superior cervical ganglion-10 is a neuronal growth-associated protein which shares significant amino acid sequence similarity with the phosphoprotein stathmin (MIM 151442).[supplied by OMIM]^[7]

Interactions

STMN2 has been shown to interact with RGS6.^[6]