STX11

Syntaxin 11, also known as STX11, is a human gene that is a member of the t-SNARE family.^[5]

STX11
Identifiers
Aliases	STX11, FHL4, HLH4, HPLH4, syntaxin 11
External IDs	OMIM: 605014; MGI: 1921982; HomoloGene: 2792; GeneCards: STX11; OMA:STX11 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q24.2 Start 144,150,517 bp[1] End 144,191,939 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A2 Start 12,813,953 bp[2] End 12,840,042 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte granulocyte blood bone marrow bone marrow cells right lung lower lobe of lung upper lobe of left lung subcutaneous adipose tissue spleen Top expressed in granulocyte blood gastrula transitional epithelium of urinary bladder lumbar spinal ganglion lens bone marrow decidua spleen right lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding SNARE binding SNAP receptor activity Cellular component integral component of membrane plasma membrane Golgi apparatus SNARE complex membrane synaptic vesicle endomembrane system presynaptic membrane presynaptic active zone membrane Biological process protein transport vesicle docking synaptic vesicle fusion to presynaptic active zone membrane membrane fusion vesicle-mediated transport intracellular protein transport exocytosis vesicle fusion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8676 74732 Ensembl ENSG00000135604 ENSMUSG00000039232 UniProt O75558 Q9D3G5 RefSeq (mRNA) NM_003764 NM_001163590 NM_001163591 NM_029075 RefSeq (protein) NP_003755 NP_001157062 NP_001157063 NP_083351 Location (UCSC) Chr 6: 144.15 – 144.19 Mb Chr 10: 12.81 – 12.84 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

STX11 has been shown to interact with SNAP25^[6][7] and SNAP23.^[6][8]

See also

• Hemophagocytic lymphohistiocytosis
• Peutz–Jeghers syndrome