SULT4A1

Sulfotransferase 4A1 is an enzyme that in humans is encoded by the SULT4A1 gene.^[5][6]

SULT4A1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZD1
Identifiers
Aliases	SULT4A1, BR-STL-1, BRSTL1, DJ388M5.3, NST, SULTX3, hBR-STL-1, sulfotransferase family 4A member 1
External IDs	OMIM: 608359; MGI: 1888971; HomoloGene: 49378; GeneCards: SULT4A1; OMA:SULT4A1 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.31 Start 43,824,509 bp[1] End 43,862,513 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E2 Start 83,960,298 bp[2] End 83,989,955 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right frontal lobe prefrontal cortex Brodmann area 9 middle temporal gyrus Brodmann area 10 right hemisphere of cerebellum primary visual cortex cingulate gyrus anterior cingulate cortex frontal pole Top expressed in medial dorsal nucleus medial vestibular nucleus superior frontal gyrus medial geniculate nucleus lateral geniculate nucleus primary visual cortex dentate gyrus of hippocampal formation granule cell deep cerebellar nuclei pontine nuclei primary motor cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity sulfotransferase activity protein binding aryl sulfotransferase activity identical protein binding Cellular component cytoplasm cytosol Biological process sulfur compound metabolic process steroid metabolic process 3'-phosphoadenosine 5'-phosphosulfate metabolic process lipid metabolism biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25830 29859 Ensembl ENSG00000130540 ENSMUSG00000018865 UniProt Q9BR01 P63046 RefSeq (mRNA) NM_014351 NM_176874 NM_013873 NM_001356515 RefSeq (protein) NP_055166 NP_038901 NP_001343444 Location (UCSC) Chr 22: 43.82 – 43.86 Mb Chr 15: 83.96 – 83.99 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia.^[6]