Small nuclear ribonucleoprotein polypeptide C

U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene.^[5][6][7]

SNRPC
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2VRD, 3CW1, 4PJO
Identifiers
Aliases	SNRPC, U1C, Yhc1, Small nuclear ribonucleoprotein polypeptide C
External IDs	OMIM: 603522; MGI: 109489; HomoloGene: 136764; GeneCards: SNRPC; OMA:SNRPC - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.31 Start 34,757,505 bp[1] End 34,773,857 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 28,057,124 bp[2] End 28,070,942 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart left testis right testis right auricle of heart left ventricle mucosa of transverse colon ventricular zone ganglionic eminence muscle of thigh gastrocnemius muscle Top expressed in yolk sac ventricular zone embryo morula embryo neural layer of retina muscle of thigh granulocyte blastocyst lip More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein homodimerization activity zinc ion binding metal ion binding protein binding single-stranded RNA binding nucleic acid binding U1 snRNA binding pre-mRNA 5'-splice site binding U1 snRNP binding RNA binding mRNA binding Cellular component Cajal body prespliceosome U1 snRNP nucleus commitment complex nucleoplasm U2-type prespliceosome Biological process spliceosomal snRNP assembly mRNA 5'-splice site recognition mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6631 20630 Ensembl ENSG00000124562 ENSMUSG00000024217 UniProt P09234 Q62241 RefSeq (mRNA) NM_003093 NM_011432 RefSeq (protein) NP_003084 NP_035562 Location (UCSC) Chr 6: 34.76 – 34.77 Mb Chr 17: 28.06 – 28.07 Mb PubMed search [3] [4]
Wikidata
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Interactions

Small nuclear ribonucleoprotein polypeptide C has been shown to interact with Ewing sarcoma breakpoint region 1.^[8]