Small nuclear ribonucleoprotein polypeptide E

Small nuclear ribonucleoprotein E is a protein that in humans is encoded by the SNRPE gene.^[4][5][6]

SNRPE
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3CW1, 3PGW, 3S6N, 4F7U, 4PJO, 4V98, 4WZJ, 3JCR
Identifiers
Aliases	SNRPE, B-raf, HYPT11, SME, Sm-E, Small nuclear ribonucleoprotein polypeptide E, snRNP-E
External IDs	OMIM: 128260; MGI: 3650419; HomoloGene: 136765; GeneCards: SNRPE; OMA:SNRPE - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 203,861,599 bp[1] End 203,871,152 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence ventricular zone left ovary right ovary olfactory zone of nasal mucosa body of pancreas canal of the cervix ectocervix body of uterus mucosa of transverse colon n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding RNA binding Cellular component cytoplasm SMN-Sm protein complex cytosol catalytic step 2 spliceosome U12-type spliceosomal complex nucleoplasm methylosome U7 snRNP small nuclear ribonucleoprotein complex pICln-Sm protein complex telomerase holoenzyme complex spliceosomal complex U4 snRNP nucleus U5 snRNP U2 snRNP U4/U6 x U5 tri-snRNP complex precatalytic spliceosome U1 snRNP U2-type catalytic step 2 spliceosome U2-type precatalytic spliceosome Biological process hair cycle mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing spliceosomal snRNP assembly spliceosomal complex assembly histone mRNA metabolic process import into nucleus RNA splicing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6635 102632439 Ensembl ENSG00000182004 n/a UniProt P62304 n/a RefSeq (mRNA) NM_001304464 NM_003094 NM_001328637 NM_001328638 n/a RefSeq (protein) NP_001291393 NP_001315566 NP_001315567 NP_003085 n/a Location (UCSC) Chr 1: 203.86 – 203.87 Mb n/a PubMed search [2] [3]
Wikidata
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Interactions

Small nuclear ribonucleoprotein polypeptide E has been shown to interact with DDX20^[7] and Small nuclear ribonucleoprotein polypeptide F.^[8]