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Syntaphilin
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
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Syntaphilin is a protein that in humans is encoded by the SNPH gene. [5]
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Function
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.
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References
Further reading
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