TAGLN2

Transgelin-2 is a protein that in humans is encoded by the TAGLN2 gene.^[5][6]

TAGLN2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WYM
Identifiers
Aliases	TAGLN2, HA1756, transgelin 2
External IDs	OMIM: 604634; MGI: 1312985; HomoloGene: 20789; GeneCards: TAGLN2; OMA:TAGLN2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.2 Start 159,918,107 bp[1] End 159,925,507 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 H3|1 79.89 cM Start 172,327,614 bp[2] End 172,334,947 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in upper lobe of left lung right lung monocyte granulocyte islet of Langerhans ventricular zone skin of abdomen mucosa of transverse colon minor salivary glands gallbladder Top expressed in pyloric antrum epithelium of stomach mucous cell of stomach lip tail of embryo right lung yolk sac right lung lobe esophagus left lung More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding cadherin binding Cellular component vesicle extracellular exosome extracellular region cytosol Biological process epithelial cell differentiation platelet degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8407 21346 Ensembl ENSG00000158710 ENSMUSG00000026547 UniProt P37802 Q9WVA4 RefSeq (mRNA) NM_003564 NM_001277223 NM_001277224 NM_178598 RefSeq (protein) NP_001264152 NP_001264153 NP_003555 NP_848713 Location (UCSC) Chr 1: 159.92 – 159.93 Mb Chr 1: 172.33 – 172.33 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined.^[6]