TAS2R13

Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.^[5][6][7]

TAS2R13
Identifiers
Aliases	TAS2R13, T2R13, TRB3, taste 2 receptor member 13
External IDs	OMIM: 604792; MGI: 2681259; HomoloGene: 41542; GeneCards: TAS2R13; OMA:TAS2R13 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 10,907,926 bp[1] End 10,909,562 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 G1|6 64.03 cM Start 132,677,053 bp[2] End 132,677,970 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle corpus callosum Achilles tendon bone marrow cells sural nerve tonsil skeletal muscle tissue ventricular zone urinary bladder liver n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity taste receptor activity bitter taste receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process positive regulation of cytokinesis detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 50838 387349 Ensembl ENSG00000212128 ENSG00000277254 ENSG00000273457 ENSMUSG00000071150 UniProt Q9NYV9 Q7M720 RefSeq (mRNA) NM_023920 NM_207024 RefSeq (protein) NP_076409 NP_996907 Location (UCSC) Chr 12: 10.91 – 10.91 Mb Chr 6: 132.68 – 132.68 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Function

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.^[7]

See also

• Taste receptor