TAS2R5

Taste receptor type 2 member 5 is a protein that in humans is encoded by the TAS2R5 gene.^[3]

TAS2R5
Identifiers
Aliases	TAS2R5, T2R5, taste 2 receptor member 5
External IDs	OMIM: 605062; HomoloGene: 49580; GeneCards: TAS2R5; OMA:TAS2R5 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q34 Start 141,790,217 bp[1] End 141,791,367 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle right uterine tube left ovary right ovary right hemisphere of cerebellum canal of the cervix ectocervix body of uterus tibial nerve skin of abdomen n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity taste receptor activity bitter taste receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process chemosensory behavior detection of chemical stimulus involved in sensory perception of bitter taste sensory perception of taste signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54429 n/a Ensembl ENSG00000127366 n/a UniProt Q9NYW4 n/a RefSeq (mRNA) NM_018980 n/a RefSeq (protein) NP_061853 n/a Location (UCSC) Chr 7: 141.79 – 141.79 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception.^[3]

See also

• Taste receptor