TAS2R50

Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.^[5][6][7][8]

TAS2R50
Identifiers
Aliases	TAS2R50, T2R50, T2R51, TAS2R51, taste 2 receptor member 50
External IDs	OMIM: 609627; MGI: 2681304; HomoloGene: 88474; GeneCards: TAS2R50; OMA:TAS2R50 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 10,985,913 bp[1] End 10,986,912 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 G1|6 64.03 cM Start 132,754,142 bp[2] End 132,755,125 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle corpus callosum Achilles tendon epithelium of colon tonsil skeletal muscle tissue sural nerve granulocyte monocyte cerebellar hemisphere n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 259296 353165 Ensembl ENSG00000212126 ENSMUSG00000053217 UniProt P59544 Q7TQA8 RefSeq (mRNA) NM_176890 NM_181276 RefSeq (protein) NP_795371 NP_851793 Location (UCSC) Chr 12: 10.99 – 10.99 Mb Chr 6: 132.75 – 132.76 Mb PubMed search [3] [4]
Wikidata
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Function

TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.^[6] See also TAS2R10.^[8]

See also

• Taste receptor