TAS2R9

Taste receptor type 2 member 9 is a protein that in humans is encoded by the TAS2R9 gene.^[3][4][5]

TAS2R9
Identifiers
Aliases	TAS2R9, T2R9, TRB6, taste 2 receptor member 9
External IDs	OMIM: 604795; HomoloGene: 88893; GeneCards: TAS2R9; OMA:TAS2R9 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 10,809,094 bp[1] End 10,810,168 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad cell monocyte endometrium n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity taste receptor activity bitter taste receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process signal transduction response to stimulus sensory perception of taste detection of chemical stimulus involved in sensory perception of bitter taste G protein-coupled receptor signaling pathway biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 50835 n/a Ensembl ENSG00000273713 ENSG00000273086 ENSG00000121381 n/a UniProt Q9NYW1 n/a RefSeq (mRNA) NM_023917 n/a RefSeq (protein) NP_076406 n/a Location (UCSC) Chr 12: 10.81 – 10.81 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.^[5]

Polymorphisms in this gene have been associated with the perceived bitterness of sweetener acesulfame potassium.^[6]

See also

• Taste receptor