Top Qs
Timeline
Chat
Perspective
TECR
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
Remove ads
Trans-2,3-enoyl-CoA reductase is an enzyme that in humans is encoded by the TECR gene.[5]
Remove ads
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[5]
Remove ads
Clinical relevance
Mutations in this gene have been shown to cause non-syndromic mental retardation.[6]
References
Further reading
Wikiwand - on
Seamless Wikipedia browsing. On steroids.
Remove ads