TFPI2

Tissue factor pathway inhibitor 2 is a protein that in humans is encoded by the TFPI2 gene.^[5][6][7]

TFPI2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZR0
Identifiers
Aliases	TFPI2, PP5, REF1, TFPI-2, tissue factor pathway inhibitor 2
External IDs	OMIM: 600033; MGI: 108543; HomoloGene: 38194; GeneCards: TFPI2; OMA:TFPI2 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.3 Start 93,885,396 bp[1] End 93,890,753 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 A1|6 1.81 cM Start 3,962,595 bp[2] End 3,988,919 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium parietal pleura islet of Langerhans cartilage tissue retinal pigment epithelium germinal epithelium pericardium placenta beta cell gonad Top expressed in decidua left lobe of liver endothelial cell of lymphatic vessel right kidney gastrula human kidney atrioventricular valve embryo migratory enteric neural crest cell yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptidase inhibitor activity extracellular matrix structural constituent serine-type endopeptidase inhibitor activity Cellular component extracellular region extracellular matrix extracellular space Biological process hemostasis negative regulation of peptidase activity blood coagulation negative regulation of endopeptidase activity cellular response to fluid shear stress Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7980 21789 Ensembl ENSG00000105825 ENSMUSG00000029664 UniProt P48307 O35536 RefSeq (mRNA) NM_006528 NM_001271003 NM_001271004 NM_009364 NM_001381907 NM_001381908 RefSeq (protein) NP_001257932 NP_001257933 NP_006519 NP_033390 NP_001368836 NP_001368837 Location (UCSC) Chr 7: 93.89 – 93.89 Mb Chr 6: 3.96 – 3.99 Mb PubMed search [3] [4]
Wikidata
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